Immunologic Defects in Laboratory Animals 1

ISBN: 9781475703276

$119.00 $101.15

Tiselius demonstrated that the immunologically active components of immune sera migrated electrophoretically in the gamma globulin region. His findings illuminated the classic observations of Jenner regarding development of resistance to infection, and those of von Pirquet, Pasteur, and Arthus regarding the transfer and specificity of resistance. Conceptual integration of these observations provided the impetus for the present modern era of immunology. Subsequent to Tiselius’s work, multiple, rapid advances have occurred in the study of congenital and acquired immune deficiency states in mice, chickens, and humans. These studies have readily demonstrated that the immunologic ability of an organ­ ism to protect itself from environmental influences is a prerequisite for survival. Indeed, this necessity for protection from microenvironmental influences has promoted the evolu­ tionary development of immunologic diversification, namely, host dependence upon a sophisticated, multifaceted network of cells and effector mechanisms responsible for the clearance and neutralization of toxins and potentially harmful pathogens. The obligate dependence of animals upon the functional integrity of their immunologic systems is illus­ trated by the ready invasion of ubiquitous organisms when the host is in a state of immune defense derangement. Nevertheless, derangements in immune function can range from par­ tial to complete and can be compatible with survival. The consequences of such derange­ ments run the gamut from subclinical disease to inevitable mortality.

Title:
Immunologic Defects in Laboratory Animals 1
ISBN-13:
9781475703276
Author:
Publisher:
Springer US
Published Date:
20120529
Edition:
1
Binding
Paperback / softback
Pages:
380
Language:
English
Product Dim.:
10.00 H x 7.01 W (inches)

Special Offers and Promotions

Our print to order bookstore saves you money. There are currently no special offers for Immunologic Defects in Laboratory Animals 1

Editorial Reviews

Thank you for selecting our online bookstore. Currently, there are no editorial book reviews for Immunologic Defects in Laboratory Animals 1

About Pubgraphics Direct

PGDirect is an online bookstore that has embraced the concept of direct to consumer selling for self-published books, softcover and hardcover books, specialty books, children's books, hard to find books, college textbooks, print on demand books and more.

Your Cart


Fatal error: Allowed memory size of 536870912 bytes exhausted (tried to allocate 72 bytes) in /home/pgdirect/public_html/wp-includes/wp-db.php on line 1972