Solid Phase Synthesis of Thioredoxin Sequences

ISBN: 9783845428840

$63.90 $54.31

It has been nearly fifty years since the advent of solid phase method for the assembly of peptides. One of the main difficulties facing researchers in this field is that of obtaining quantities of peptides and proteins in a pure state. Isolation of proteins form natural resources can be laborious and often provides only tiny quantities. Investigations dealing with the quantitative aspects of polymer-supported reactions have shown that the insoluble support does have a significant dynamic influence on the bound substrates. An efficient polymeric support for peptdide synthesis should have optimum hydrophobic-hydrophilic balance compatible with the peptide being synthesized. This book illustrates the synthesis and characterization of a novel polymer support, polystyrene crosslinked with 1,6-hexanediol diacrylate for the successful synthesis of peptides. The compatibility of the new support is proved by synthesizing sequences of Thioredoxin, which is otherwise difficult to synthesize. Thioredoxin is a naturally occurring sulphur reducing protein containing 108 amino acids. The book is useful to researchers, scientists and academia in studying the intricacies of solid phase synthesis.

Categories: ,
Title:
Solid Phase Synthesis of Thioredoxin Sequences
ISBN-10:
3845428848
ISBN-13:
9783845428840
Author:
Jaya T. Varkey
Publisher:
LAP LAMBERT Academic Publishing
Published Date:
20110818
Edition:
1
Binding
Paperback / softback
Pages:
140
Language:
English
Product Dim.:
8.66 H x 5.91 W (inches)

Jaya T. Varkey

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