Terahertz Spectroscopy of Proteins

ISBN: 9783838121475

$96.39 $81.93

In this work, global hydration dynamics of solute molecules in water has been studied extensively by terahertz (THz) absorption spectroscopy. Hydration studies have been carried out in dynamical chemical equilibrium as well as in real-time while biochemical reactions proceeded. To characterize the role of water dynamics in a chemical reaction, a kinetic terahertz absorption (KITA) spectrometer has been developed, set up, and applied. In chemical equilibrium, model peptides based on the amino acids glycine, leucine, and tryptophan have been studied as well as native and denatured protein variants (ubiquitin) and functional enzymes (MT1-MMP). Furthermore, non-equilibrium dynamical properties of water network rearrangements has been observed by KITA spectroscopy in real-time for ubiquitin folding and for MT1-MMP-driven hydrolysis of peptide substrates. Comprehensive interpretation of the time-resolved KITA measurements has been achieved by merging KITA with state of the art real-time biophysical methods and simulations.

Categories: ,
Title:
Terahertz Spectroscopy of Proteins
ISBN-10:
3838121473
ISBN-13:
9783838121475
Author:
Benjamin Born
Publisher:
Südwestdeutscher Verlag für Hochschulschriften
Published Date:
20101103
Edition:
1
Binding
Paperback / softback
Pages:
168
Language:
English
Product Dim.:
8.66 H x 5.91 W (inches)

Benjamin Born

Special Offers and Promotions

Our print to order bookstore saves you money. There are currently no special offers for Terahertz Spectroscopy of Proteins

Editorial Reviews

Thank you for selecting our online bookstore. Currently, there are no editorial book reviews for Terahertz Spectroscopy of Proteins

About Pubgraphics Direct

PGDirect is an online bookstore that has embraced the concept of direct to consumer selling for self-published books, softcover and hardcover books, specialty books, children's books, hard to find books, college textbooks, print on demand books and more.

Your Cart